Vitamin E does not prevent Western diet-induced NASH progression and increases metabolic flux dysregulation in mice
Fatty liver involves ectopic lipid accumulation and dysregulated hepatic oxidative metabolism, which can progress to a state of elevated inflammation and fibrosis referred to as nonalcoholic steatohepatitis (NASH).The factors that control progression from simple E-Z MOBILITY steatosis to NASH are not fully known.Here, we tested the hypothesis that